Save yourself hundreds of hours trolling through the internet!
Click on the links below and go straight to the sites I use.
Except for long international flights I generally start with Rome2Rio and work out options from there.
Many of the sites that I have included in flights also offer accommodation, cars and cruises and vice versa in the accommodation section. However the way I've categorised them is how I've generally used them.
It's interesting to note that Priceline Group includes Booking.com, Agoda, Kayak, Rentalcars and OpenTable and Expedia Inc. includes Hotels.com, Travelocity, Trivago and Orbitz with CarRentals.com.
However the companies appear to operate independently and if you have an account with them you can often get a better deal than the "group" price.
Travelling by train or bus has become my preferred option as flights have become more and more time consuming and hassle.